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intestinal tuft cell
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CL_0019032 |
[A tuft cell that is part of the intestinal epithelium, characterized by a distinctive apical tuft and lateral cytospinules connecting to neighbouring cells. This cell senses luminal stimuli via taste receptors and succinate signalling, initiating type 2 immune responses through the secretion of interleukin-25 while modulating epithelial regeneration through prostaglandin synthesis. It expresses key molecular markers such as doublecortin-like kinase 1 (DCLK1) in mice (Hendel et al., 2022), and KIT proto-oncogene in humans (Huang et al., 2024). Developed from intestinal crypt stem cells, this cell requires transcription factor POU2F3 for its development.] |
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maternal placenta development
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GO_0001893 |
[Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.] |
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maternal process involved in female pregnancy
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GO_0060135 |
[A reproductive process occurring in the mother that allows an embryo or fetus to develop within it.] |
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NCBITaxon_4895
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NCBITaxon_4895 |
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embryonic placenta development
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GO_0001892 |
[The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.] |
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NCBITaxon_4896
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NCBITaxon_4896 |
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placenta development
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GO_0001890 |
[The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.] |
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integrin alpha-M (mouse)
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PR_P05555 |
[An integrin alpha-M that is encoded in the genome of mouse.] |
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NCBITaxon_4891
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NCBITaxon_4891 |
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NCBITaxon_4890
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NCBITaxon_4890 |
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liver development
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GO_0001889 |
[The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.] |
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endothelial cell morphogenesis
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GO_0001886 |
[The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.] |
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epithelial cell morphogenesis
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GO_0003382 |
[The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.] |
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insect embryonic/larval protocerebrum
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UBERON_6001925 |
[Protocerebrum of the embryo/larva.] |
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regulation of protein secretion
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GO_0050708 |
[Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.] |
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limb morphogenesis
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GO_0035108 |
[The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.] |
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insect embryonic/larval brain
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UBERON_6001920 |
[Brain of the embryo/larva.] |
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insect embryonic/larval central nervous system
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UBERON_6001919 |
[Central nervous system of the embryo/larva.] |
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insect embryonic/larval nervous system
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UBERON_6001911 |
[Nervous system of the embryo/larva.] |
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polysaccharide immune receptor activity
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GO_0001873 |
[Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.] |