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Cytochrome P-450 CYP2C19 Inhibitors
|
D27.505.519.389.335.319 |
|
|
Complement C1 Inactivator Proteins
|
D003174 |
[Serum proteins that inhibit, antagonize, or inactivate COMPLEMENT C1 or its subunits.
] |
|
Complement C1s
|
D003173 |
[A 77-kDa subcomponent of complement C1, encoded by gene C1S, is a SERINE PROTEASE existing as a proenzyme (homodimer) in the intact complement C1 complex. Upon the binding of COMPLEMENT C1Q to antibodies, the activated COMPLEMENT C1R cleaves C1s into two chains, A (heavy) and B (light, the serine protease), linked by disulfide bonds yielding the active C1s. The activated C1s, in turn, cleaves COMPLEMENT C2 and COMPLEMENT C4 to form C4b2a (CLASSICAL C3 CONVERTASE).
] |
|
Saline Waters
|
G16.500.275.725 |
|
|
Environment
|
G16.500.275 |
|
|
Complement C1
|
D003172 |
[The first complement component to act in the activation of CLASSICAL COMPLEMENT PATHWAY. It is a calcium-dependent trimolecular complex made up of three subcomponents: COMPLEMENT C1Q; COMPLEMENT C1R; and COMPLEMENT C1S at 1:2:2 ratios. When the intact C1 binds to at least two antibodies (involving C1q), C1r and C1s are sequentially activated, leading to subsequent steps in the cascade of COMPLEMENT ACTIVATION.
] |
|
Complement Pathway, Classical
|
D003171 |
[Complement activation initiated by the binding of COMPLEMENT C1 to ANTIGEN-ANTIBODY COMPLEXES at the COMPLEMENT C1Q subunit. This leads to the sequential activation of COMPLEMENT C1R and COMPLEMENT C1S subunits. Activated C1s cleaves COMPLEMENT C4 and COMPLEMENT C2 forming the membrane-bound classical C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and the assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.
] |
|
Eleutherococcus
|
B01.650.940.800.575.912.250.087.374 |
|
|
Araliaceae
|
B01.650.940.800.575.912.250.087 |
|
|
Receptors, Adrenergic, alpha-1
|
D12.776.543.750.720.330.300.300.100 |
|
|
Physical Therapists
|
M01.526.485.790 |
|
|
Pituitary Gland, Anterior
|
A08.186.211.200.317.357.352.435.500.500 |
|
|
Corneal Dystrophy, Juvenile Epithelial of Meesmann
|
C11.204.236.218 |
|
|
Corneal Dystrophies, Hereditary
|
C11.204.236 |
|
|
Mycobacterium avium-intracellulare Infection
|
C01.150.252.410.040.552.475.495 |
|
|
Mycobacterium Infections, Nontuberculous
|
C01.150.252.410.040.552.475 |
|
|
Delftia
|
D042742 |
[A genus of gram-negative, strictly aerobic chemoorganotrophic bacteria, in the family COMAMONADACEAE.
] |
|
Complement C3 Nephritic Factor
|
D003178 |
[An IgG autoantibody against the ALTERNATIVE PATHWAY C3 CONVERTASE, found in serum of patients with MESANGIOCAPILLARY GLOMERULONEPHRITIS. The binding of this autoantibody to C3bBb stabilizes the enzyme thus reduces the actions of C3b inactivators (COMPLEMENT FACTOR H; COMPLEMENT FACTOR I). This abnormally stabilized enzyme induces a continuous COMPLEMENT ACTIVATION and generation of C3b thereby promoting the assembly of MEMBRANE ATTACK COMPLEX and cytolysis.
] |
|
Coxa Valga
|
C05.116.214.750.500 |
|
|
Bone Retroversion
|
C05.116.214.750 |
|
