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transcriptional attenuation
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GO_0031555 |
[A negative regulation of gene expression mechanism by which bacteria and archae can direct RNA polymerase to prematurely terminate transcription in response to a specific metabolic signal.] |
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transcriptional attenuation by ribosome
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GO_0031556 |
[A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch.] |
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obsolete induction of programmed cell death in response to chemical stimulus
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GO_0031557 |
[OBSOLETE. A process which directly activates any of the steps required for programmed cell death as a result of a chemical stimulus.] |
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obsolete induction of apoptosis in response to chemical stimulus
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GO_0031558 |
[OBSOLETE. Any process that directly activates any of the steps required for cell death by apoptosis as a result of a chemical stimulus.] |
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hemidesmosome assembly
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GO_0031581 |
[Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.] |
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replication fork arrest at rDNA repeats
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GO_0031582 |
[A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer.] |
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maintenance of rDNA
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GO_0043007 |
[Any process involved in sustaining the fidelity and copy number of rDNA repeats.] |
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replication fork arrest
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GO_0043111 |
[Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.] |
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phospholipase D-activating G protein-coupled receptor signaling pathway
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GO_0031583 |
[A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase D (PLD) and a subsequent increase in the intracellular concentration of phosphatidic acid (PA).] |
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obsolete activation of phospholipase D activity
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GO_0031584 |
[OBSOLETE. Any process that initiates the activity of inactive phospholipase D.] |
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obsolete regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
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GO_0031585 |
[OBSOLETE. Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.] |
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obsolete negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
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GO_0031586 |
[OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.] |
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obsolete positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
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GO_0031587 |
[OBSOLETE. Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.] |
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nucleotide-activated protein kinase complex
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GO_0031588 |
[A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).] |
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mitotic G1 DNA damage checkpoint signaling
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GO_0031571 |
[A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage checkpoint.] |
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GO_0031572
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GO_0031572 |
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mitotic intra-S DNA damage checkpoint signaling
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GO_0031573 |
[A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression.] |
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GO_0031574
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GO_0031574 |
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GO_0031575
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GO_0031575 |
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GO_0031576
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GO_0031576 |
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