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novobiocin biosynthetic process
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GO_0043642 |
[The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase.] |
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biphenyl 2,3-dioxygenase activity
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GO_0018687 |
[Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+.] |
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oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
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GO_0016708 |
[Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor.] |
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obsolete tetracycline metabolic process
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GO_0043643 |
[OBSOLETE. The chemical reactions and pathways involving tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).] |
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obsolete DDT 2,3-dioxygenase activity
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GO_0018688 |
[OBSOLETE. Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT.] |
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obsolete naphthalene disulfonate 1,2-dioxygenase activity
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GO_0018689 |
[OBSOLETE. Catalysis of the reaction: (1/2)-unsubstituted naphthalenoid-(2/1)-sulfonate + 2 H+ + 2 e- + O2 = 1,2-dihydroxynaphthalene derivative + HSO3(-). Substrates include naphthalene-1,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate), naphthalene-1-sulfonate (forms 1,2-dihydroxynaphthalene), naphthalene-2,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate) and naphthalene-2-sulfonate (forms 1,2-dihydroxynaphthalene).] |
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apyrase activity
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GO_0004050 |
[Catalysis of the reaction: a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate. This reaction consists of two distinct successive phosphate-releasing steps, with NDPs as intermediates. Apyrases are active against both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs).] |
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arachidonate 5-lipoxygenase activity
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GO_0004051 |
[Catalysis of the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = H2O + leukotriene A4.] |
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arachidonate 12(S)-lipoxygenase activity
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GO_0004052 |
[Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.] |
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arginase activity
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GO_0004053 |
[Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea.] |
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arginine kinase activity
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GO_0004054 |
[Catalysis of the reaction: L-arginine + ATP = N(omega)-phospho-L-arginine + ADP + 2 H+.] |
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argininosuccinate synthase activity
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GO_0004055 |
[Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate.] |
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argininosuccinate lyase activity
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GO_0004056 |
[Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.] |
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arginyl-tRNA--protein transferase activity
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GO_0004057 |
[Catalysis of the reaction: an N-terminal L-alpha-aminoacyl-[protein] + L-arginyl-tRNA(Arg) = H+ + N-terminal L-arginyl-L-amino acid-[protein] + tRNA(Arg).] |
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aromatic-L-amino-acid decarboxylase activity
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GO_0004058 |
[Catalysis of the reaction: L-amino acid + H+ = R-H + CO2.] |
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polyadenylation-dependent RNA catabolic process
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GO_0043633 |
[The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3'-end of the target RNA.] |
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aralkylamine N-acetyltransferase activity
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GO_0004059 |
[Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine.] |
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polyadenylation-dependent ncRNA catabolic process
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GO_0043634 |
[The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.] |
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methylnaphthalene catabolic process
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GO_0043635 |
[The chemical reactions and pathways resulting in the breakdown of methylnaphthalene, an organic compound, C10H7CH3, obtained from coal tar.] |
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bisphenol A catabolic process
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GO_0043636 |
[The chemical reactions and pathways resulting in the breakdown of bisphenol A, 4,4'-(propane-2,2-diyl)diphenol, a synthetic, aromatic organic compound used as a monomer in the manufacture of polycarbonate plastic and in the manufacture of epoxy resins.] |