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negative regulation of signal transduction
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GO_0009968 |
[Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.] |
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GO_0030179
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GO_0030179 |
|
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pyridoxal phosphate binding
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GO_0030170 |
[Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.] |
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vitamin B6 binding
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GO_0070279 |
[Binding to a vitamin B6 compound: pyridoxal, pyridoxamine, pyridoxine, or the active form, pyridoxal phosphate.] |
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anion binding
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GO_0043168 |
[Binding to an anion, a charged atom or group of atoms with a net negative charge.] |
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voltage-gated proton channel activity
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GO_0030171 |
[Enables the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.] |
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proton channel activity
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GO_0015252 |
[Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.] |
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obsolete calpain inhibitor activity
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GO_0030161 |
[OBSOLETE. Stops, prevents or reduces the activity of the enzyme calpain, which catalyzes of the preferential cleavage of Tyr-Xaa, Met-Xaa or Arg-Xaa with Leu or Val as the P2 residue.] |
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regulation of proteolysis
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GO_0030162 |
[Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.] |
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regulation of protein metabolic process
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GO_0051246 |
[Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.] |
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protein catabolic process
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GO_0030163 |
[The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.] |
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macromolecule catabolic process
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GO_0009057 |
[The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.] |
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protein metabolic process
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GO_0019538 |
[The chemical reactions and pathways involving a protein. Includes protein modification.] |
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protein denaturation
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GO_0030164 |
[Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds.] |
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PDZ domain binding
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GO_0030165 |
[Binding to a PDZ domain of a protein, a domain found in diverse signaling proteins.] |
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proteoglycan biosynthetic process
|
GO_0030166 |
[The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.] |
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glycoprotein biosynthetic process
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GO_0009101 |
[The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.] |
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glycoprotein catabolic process
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GO_0006516 |
[The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.] |
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platelet activation
|
GO_0030168 |
[A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.] |
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cell activation
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GO_0001775 |
[A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell.] |