All terms in GO

Label Id Description
canonical NF-kappaB signal transduction GO_0007249 [An intracellular signaling cassette characterized by the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB, also known as the canonical NF-kappaB signaling cascade. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. The canonical NF-kappaB pathway is mainly stimulated by proinflammatory cytokines such as IL-1beta, tumor necrosis factor (TNF)-alpha, antigen ligands, and toll-like receptors (TLRs).]
protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity GO_0022879 [Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.]
obsolete nuclear translocation of MAPK (mating sensu Saccharomyces) GO_0007248 [OBSOLETE. Movement of a MAP kinase to the nucleus in the context of transduction of mating pheromone signal, as described for Saccharomyces.]
protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity GO_0022878 [Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sucrose(out) = protein histidine + sucrose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.]
protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity GO_0022877 [Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.]
negative regulation of protein export from nucleus GO_0046826 [Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm.]
maintenance of protein location in nucleus GO_0051457 [Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus.]
regulation of protein export from nucleus GO_0046825 [Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm.]
protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity GO_0022876 [Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.]
negative regulation of RNA import into nucleus GO_0046829 [Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus.]
protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity GO_0022871 [Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbose(out) = protein histidine + sorbose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.]
protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity GO_0022870 [Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannose(out) = protein histidine + mannose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.]
4-amino-4-deoxychorismate synthase activity GO_0046820 [Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate.]
protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity GO_0022875 [Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.]
protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity GO_0022874 [Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + cellobiose(out) = protein histidine + cellobiose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.]
protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity GO_0022873 [Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + maltose(out) = protein histidine + maltose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.]
extrachromosomal DNA GO_0046821 [DNA structures that are not part of a chromosome.]
protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity GO_0022872 [Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.]
regulation of cytoplasmic translational fidelity GO_0140018 [Any process that modulates the ability of the cytoplasmic translational apparatus to interpret the genetic code.]
histone H3K18cr reader activity GO_0140017 [A histone reader that recognizes a histone H3 crotonylated at lysine 18.]