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Apremilast
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DB05676 |
[Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as [Roflumilast] and [Crisaborole].[A181244,L7495] Initially approved in 2014, it is marketed by Celgene.[L7501] In July 2019, apremilast was granted a new FDA approval for the treatment of oral ulcers associated with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and central nervous system inflammation.[A181216]] |
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EP-2104R
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DB05675 |
[EP-2104R is an imaging pharmaceutical under development for the detection of blood clots. It is the first targeted high-resolution technique designed to visualize blood clots directly. It is being developed by EPIX Pharmaceuticals, Inc.] |
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Glyoxylic acid
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DB04343 |
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Phenylalanine-N-Sulfonamide
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DB03012 |
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N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosamine
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DB03013 |
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Thiodigalactoside
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DB04396 |
[Thiodigalactoside is a solid. This compound belongs to the dihexoses. These are disaccharides containing two hexose carbohydrates. This medication is known to target galectin-1, heat-labile enterotoxin b chain, neurocan core protein, and lactose permease.] |
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7-Nitroindazole-2-Carboxamidine
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DB03065 |
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D-Lactic acid
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DB03066 |
[A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)] |
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Alpha-D-Glucose-1-Phosphate-6-Vanadate
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DB04397 |
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3-Nitro-4-(2-Oxo-Pyrrolidin-1-Yl)-Benzenesulfonamide
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DB04394 |
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N-[(2S,3S)-4-[2-[(5S)-3a,4,5,6,7,7a-Hexahydro-1,3-benzodioxol-5-yl]ethyl-[3-(1,3-dioxoisoindol-2-yl)propanoyl]amino]-3-hydroxy-1-phenylbutan-2-yl]-3,5-dimethoxy-4-phenylmethoxybenzamide
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DB03063 |
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3-Decyl-2,5-Dioxo-4-Hydroxy-3-Pyrroline
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DB03064 |
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Phosphoaminophosphonic Acid-Adenylate Ester
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DB04395 |
[5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation. [PubChem]] |
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Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone]
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DB04392 |
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(R)-N-(1-Methyl-Hexyl)-Formamide
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DB03061 |
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(1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone
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DB03062 |
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Soneclosan
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DB04393 |
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Sri-9662
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DB03060 |
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Aeruginosin 98-B
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DB04391 |
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BMS-919373
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DB15047 |
[BMS-919373 is under investigation in clinical trial NCT02153437 (Study of the Effects of BMS-919373 on the Electrical Activity of the Heart Using Pacemakers).] |