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Necitumumab
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DB09559 |
[Necitumumab is an intravenously administered recombinant monoclonal IgG1 antibody used in the treatment of non-small cell lung cancer (NSCLC) as an EGFR antagonist. It functions by binding to epidermal growth factor receptor (EGFR) and prevents binding of its ligands, a process that is involved in cell proliferation, metastasis, angiogenesis, and malignant progression. Binding of necitumumab to EGFR induces receptor internalization and degradation, thereby preventing further activation of EGFR which is beneficial in NSCLC as many patients have increased protein expression of EGFR. Necitumumab is approved for use in combination with cisplatin and gemcitabine as a first-line treatment for metastatic squamous non-small cell lung cancer (NSCLC).] |
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3,3'-diindolylmethane
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DB11875 |
[Diindolylmethane has been used in trials studying the prevention and treatment of SLE, Prostate Cancer, Cervical Dysplasia, Stage I Prostate Cancer, and Stage II Prostate Cancer, among others.] |
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[N-(3-dibenzylcarbamoyl-oxiranecarbonyl)-hydrazino]-acetic acid
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DB08229 |
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Orange
|
DB10549 |
[Orange allergenic extract is used in allergenic testing.] |
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Dusquetide
|
DB11879 |
[Dusquetide has been used in trials studying the treatment of Oral Mucositis.] |
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Onion
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DB10548 |
[Onion allergenic extract is used in allergenic testing.] |
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RG-4733
|
DB11870 |
[Ro4929097 has been used in trials studying the treatment of Sarcoma, LYMPHOMA, Neoplasms, Wilm's Tumor, and OSTEOSARCOMA, among others.] |
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Crocin
|
DB11874 |
[Crocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia.] |
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Cow milk
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DB10543 |
[Cow milk allergenic extract is used in allergenic testing.] |
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Verinurad
|
DB11873 |
[Verinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia, and Gout and Asymptomatic Hyperuricemia.] |
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Goat milk
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DB10542 |
[Goat milk allergenic extract is used in allergenic testing.] |
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Lobster
|
DB10541 |
[Lobster allergenic extract is used in allergenic testing.] |
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ZD-6126
|
DB11872 |
[ZD6126 has been used in trials studying the treatment of Kidney Neoplasms, Colorectal Neoplasms, Metastases, Neoplasm, and Carcinoma, Renal Cell.] |
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PF-00610355
|
DB11871 |
[PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others.] |
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Lima bean
|
DB10540 |
[Lima bean allergenic extract is used in allergenic testing.] |
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(8alpha,10alpha,13alpha,17beta)-17-[(4-hydroxyphenyl)carbonyl]androsta-3,5-diene-3-carboxylic acid
|
DB08220 |
|
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Thonzonium
|
DB09552 |
[Thonzonium is a monocationic surface-active agent with surfactant and detergent properties. It is widely used as an additive to in ear and nasal drops to enhance dispersion and penetration of cellular debris and exudate, thereby promoting tissue contact of the administered medication. A common pharmaceutical formulation of thonzonium bromide is cortisporin-TC ear drops. It is also reported that thonzonium also confers an antifungal property and antiresorptive effect on bone.] |
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Desoxyribonuclease
|
DB09551 |
[Desoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into fragments approaching the size of tetranucleotides without the release of free phosphoric acid. The enzyme's cofactor is reported to be magnesium (or manganese) ions, although the optimal concentration of the ion is independent of the enzyme concentration [A31251].] |
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N-{4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]PHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE
|
DB08221 |
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METHOXYUNDECYLPHOSPHINIC ACID
|
DB08222 |
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