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Obinutuzumab
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DB08935 |
[Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to treat patients with untreated chronic lymphocytic leukemia. It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. There is a black box warning of fatal Hepatitis B Virus (HBV) reactivation and fatal Progressive Multifocal Leukoencephalopathy (PML).] |
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Chlorcyclizine
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DB08936 |
[Chlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms. Chlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can be used as an antiemetic.] |
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2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE
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DB07605 |
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6-(3,4-DIHYDROXYBENZYL)-3-ETHYL-1-(2,4,6-TRICHLOROPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4(5H)-ONE
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DB07606 |
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TAS-102
|
DB08937 |
[TAS-102 (Taiho Pharma USA, Inc.) is an anti-cancer drug under development and in stage 3 clinical trials for the treatment of colorectal cancer. It is composed of the thymidine phosphorylase inhibitor (TPI) tipiracil and the cytotoxin trifluridine. Trifluridine inhibits tumor growth by being incorporated into DNA during DNA synthesis. Tipiracil prevents trifluridine from being broken down when taken orally. ] |
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4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE
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DB07607 |
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Magaldrate
|
DB08938 |
[Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.] |
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N-(5-{[(2S)-4-amino-2-(3-chlorophenyl)butanoyl]amino}-1H-indazol-3-yl)benzamide
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DB07608 |
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Letosteine
|
DB08939 |
[Letosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.] |
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N,N-DIMETHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE
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DB07609 |
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NAPHTHALENE-1,2-DIOL
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DB07610 |
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Isoxsuprine
|
DB08941 |
[A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.] |
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DECANE-1-THIOL
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DB07611 |
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Isoxicam
|
DB08942 |
[Isoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States.] |
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6-(3-AMINOPHENYL)-N-(TERT-BUTYL)-2-(TRIFLUOROMETHYL)QUINAZOLIN-4-AMINE
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DB07612 |
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Isoconazole
|
DB08943 |
[Isoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.] |
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3-phenyl-5-(1H-pyrazol-3-yl)isoxazole
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DB07613 |
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Isoaminile
|
DB08944 |
[Isoaminile, an antitussive drug with a structure similar to methadone, is also an anticholinergic with both antimuscarinic and antinicotinic properties.] |
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PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE
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DB07614 |
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Iotroxic acid
|
DB08945 |
[Iotroxic acid is a contrast medium molecule.] |
