|
protein-containing complex
|
GO_0032991 |
[A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.] |
|
material entity
|
BFO_0000040 |
|
|
amyloid deposition
|
MPATH_34 |
[Extracellular deposition of amyloid protein.] |
|
pathological entity
|
MPATH_0 |
[Pathological structure or process] |
|
Diffusion Tensor Imaging
|
NCIT_C64862 |
[A type of diffusion-weighted magnetic resonance imaging (DW-MRI) that maps the diffusion of water in three dimensions, the principal purpose of which is to image the white matter of the brain, specifically measuring the anisotropy, location, and orientation of the neural tracts, which can demonstrate microstructural changes or differences with neuropathology and treatment.] |
|
Magnetic Resonance Imaging
|
NCIT_C16809 |
[Imaging that uses radiofrequency waves and a strong magnetic field rather than x-rays to provide detailed pictures of internal organs and tissues. The technique is valuable for the diagnosis of many pathologic conditions, including cancer, heart and vascular disease, stroke, and joint and musculoskeletal disorders.] |
|
continuant
|
BFO_0000002 |
|
|
entity
|
BFO_0000001 |
|
|
drug development tool
|
BMONT_0000030 |
[A biomarker, clinical outcome assesment, or any other method, material, or measure
determined to aid drug development and regulatory review (FD&C Act, section 507(e)(5)).] |
|
occurrent
|
BFO_0000003 |
|
|
Thing
|
Thing |
|
|
regenerative capacity
|
BMONT_0000149 |
[Regenerative capacity is a complex trait dependent on the ability to access high-fidelity morphogenetic programmes after injury. It is distributed unequally among species and, within individuals, among their tissues.] |
|
specimen
|
OBI_0100051 |
[A material entity that has the specimen role.] |
|
GrimAge2
|
BMONT_0000156 |
[GrimAge2 is an updated version of the original GrimAge, which is a DNA methylation-based biological clock developed to estimate biological age and predict mortality risk.] |
|
epigenetic clock
|
BMONT_0000139 |
[Epigenetic clocks are mathematically derived age estimators that are based on combinations of methylation values that change with age at specific CpGs in the genome.] |
|
DNA methylation risk score
|
BMONT_0000157 |
[DNA methylation-based risk score is a relatively recent metric used in research to assess biological age and associated health risks based on DNA methylation patterns. It evaluates the methylation levels at specific sites in the genome that are linked to various health outcomes, effectively providing a score that reflects the biological age of an individual as opposed to their chronological age.] |
|
pace of aging computed from the epigenome
|
BMONT_0000158 |
[Pace of Aging Computed from the Epigenome is a biomarker developed to assess the biological aging process based on DNA methylation patterns. Unlike other aging measures that focus on chronological age, DunedinPACE specifically evaluates how quickly or slowly an individual is aging by analyzing chemical tags (methylation marks) on DNA in white blood cells.] |
|
MetaboHealth score
|
BMONT_0000159 |
[The MetaboHealth score is a metabolomics-based health assessment that utilizes a panel of serum metabolic markers to evaluate an individual's metabolic health and its association with health outcomes.] |
|
total cholesterol measurement
|
EFO_0004574 |
[A total cholesterol measurement is the quantification of cholesterol in blood, total cholesterol is defined as the sum of HDL, LDL, and VLDL.] |
|
BloodAge
|
BMONT_0000152 |
[BloodAge refers to a biological age estimation method that uses a blood-based proteomic signature to assess how old a person is biologically, as opposed to their chronological age. By analyzing the levels of specific proteins in the blood, this method predicts a person's biological aging and potential risk for age-related diseases.] |