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Respiratory Rate
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SCDO_0000993 |
[The number of times an organism breathes with the lungs (respiration) per unit time, usually per minute.] |
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staging biomarker
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BMONT_0000010 |
[A biomarker that distinguishes between different stages of chronic disease.] |
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efficacy biomarker
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BMONT_0000011 |
[A biomarker that predicts a beneficial effect of a given treatment.] |
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neutrophil gelatinase-associated lipocalin
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PR_000009725 |
[A protein that is a translation product of the human LCN2 gene or a 1:1 ortholog thereof.] |
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toxicity biomarker
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BMONT_0000013 |
[A biomarker that reports to the toxic effect of a drug on an in vitro or in vivo system.] |
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COX proportional hazards regression model
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BMONT_0000014 |
[The Cox proportional hazards regression model, often referred to as Cox regression or just proportional hazards model, is a statistical technique used to analyze the relationship between the survival time of subjects and predictor variables. It's commonly employed in survival analysis, a branch of statistics that deals with time-to-event data, such as time until death or time until recurrence of a disease.] |
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leukocyte telomere length
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BMONT_0000136 |
[Leukocyte telomere length (LTL) is a complex genetic trait. It shortens with age and is associated with a host of aging-related disorders.] |
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sleep latency
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EFO_0005280 |
[amount of time, usually recorded in minutes, between going to bed and falling asleep] |
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mitochondrial function
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BMONT_0000137 |
[Mitochondrial function refers to the various vital processes performed by mitochondria, which are the energy-producing organelles in cells.] |
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psoriasis
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DOID_8893 |
[A skin disease that is characterized by patches of thick red skin and silvery scales.] |
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context of use
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BMONT_0000016 |
[The context of use is a concise description of a biomarker's specified use in drug developement.] |
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interstitial lung disease
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DOID_3082 |
[A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.] |
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hepatitis B virus infection
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EFO_0004197 |
[A viral infection caused by the hepatitis B virus., INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.] |
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biomarker validation
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BMONT_0000017 |
[Validation is a process to establish that the performance of a test, tool, or instrument is acceptable for its intended purpose.] |
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analitical validation
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BMONT_0000018 |
[Analytical validation aims to establish the performance characteristics of a biomarker including sensitivity, specificity, accuracy, precision, inter-laboratory reproducibility and other relevant performance characteristics following a pre-specified protocol.] |
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clinical validation
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BMONT_0000019 |
[Clinical validation aims to establish an association between the biomarker and the endpoint of interest and to demonstrate the usefulness of the biomarker. Clinical validation relies on external validation and can be done by retrospective use of clinical trial data or by prospective clinical trials. Retrospective use of clinical trial data is a form of external clinical validation where the biomarker evaluation is not part of the original study design.] |
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wild type genotype
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EFO_0005168 |
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genotype
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EFO_0000513 |
[The total sum of the genetic information of an organism that is known and relevant to the experiment being performed, including chromosomal, plasmid, viral or other genetic material which has been introduced into the organism either prior to or during the experiment.] |
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maximal voluntary ventilation
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EFO_0008431 |
[Qunatification of the maximum volume of air that an organism can breathe in and out during a specified period of time, often 1 minute.] |
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peripheral artery disease
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DOID_0050830 |
[An artery disease that is characterized by build up of plaque in the arteries that carry blood to your head, organs, and limbs.] |