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biological role
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CHEBI_24432 |
[A role played by the molecular entity or part thereof within a biological context.] |
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role
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BFO_0000023 |
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object
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BFO_0000030 |
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Proliferation
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NCIT_C28378 |
[Multiplying or increasing in number.] |
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tumor size
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EFO_0004134 |
[The physical size of a tumor.] |
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nephrotic syndrome
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EFO_0004255 |
[A collection of symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction., A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.] |
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immunohistochemistry
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OBI_0001986 |
[An immunostaining assay to detect and potentially localize antigens within the cells of a tissue section.] |
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neurogranin
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PR_000011426 |
[A protein that is a translation product of the human NRGN gene or a 1:1 ortholog thereof.] |
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hepatitis C virus infection
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EFO_0003047 |
[A Hepacivirus infectious disease which is a chronic bloodborne infectious disease caused by Hepatitis C virus. The symptoms include fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain and jaundice., A viral infection caused by the hepatitis C virus., A viral hepatitis and is_a Hepacivirus infectious disease, that results_in inflammation located_in liver, has_agent Hepatitis C virus, which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice., A Hepacivirus infectious disease and is_a viral hepatitis that results_in inflammation located_in liver, has_agent Hepatitis C virus, which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.] |
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blood specimen
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OBI_0000655 |
[a material entity derived from a portion of blood collected from an organism] |
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metastasis
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EFO_0009708 |
[The spread or migration of cancer cells from one part of the body (where they first appeared) to another. The secondary tumor contains cells that are like those in the original (primary) tumor. [ NCI ]] |
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metastatic neoplasm
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EFO_0009709 |
[A tumor that has spread from its original (primary) site of growth to another site, close to or distant from the primary site. Metastasis is characteristic of advanced malignancies, but in rare instances can be seen in neoplasms lacking malignant morphology.] |
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Ki-67 Antigen
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OMIT_0019447 |
[definition
A CELL CYCLE and tumor growth marker which can be readily detected using IMMUNOCYTOCHEMISTRY methods. Ki-67 is a nuclear antigen present only in the nuclei of cycling cells.] |
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Positron Emission Tomography
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NCIT_C17007 |
[A technique for measuring the gamma radiation produced by collisions of electrons and positrons (anti-electrons) within living tissue. In positron emission tomography (PET), a subject is given a dose of a positron-emitting radionuclide attached to a metabolically active substance (for example, 2-fluoro-2-deoxy-D-glucose (FDG), which is similar to a naturally occurring sugar, glucose, with the addition of a radioactive fluorine atom). When living tissue containing the positron emitter is bombarded by electrons, gamma radiation produced by collisions of electrons and positrons is detected by a scanner, revealing in fine detail the tissue location of the metabolically-active substance administered.] |
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procedure
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AFRE_0000002 |
[A procedure is plan containing multiple activities that are intended to be executed in an order following a procedure specification. [Allotrope]] |
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breast cancer
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DOID_1612 |
[A thoracic cancer that originates in the mammary gland.] |
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N(omega),N(omega)-dimethyl-L-arginine
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CHEBI_17929 |
[A L-arginine derivative having two methyl groups both attached to the primary amino moiety of the guanidino group.] |
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gene
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OGG_0000000002 |
[A gene is a material entity that represents the entire DNA sequence required for synthesis of a functional protein or RNA molecule. ] |
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tumor necrosis factor-alpha
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EFO_0003271 |
[Tumor necrosis factor (TNF, cachexin or cachectin formerly known as tumor necrosis factor-alpha or TNF-α) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well.] |
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impaired renal function disease
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MONDO_0001343 |
[Any disease in which the causes of the disease is a perturbation of the kidney leading to its dysfunction.] |